DATASHEET
Formulation
Cream colored solid
Storage:
-20°C
Product Information:
Dihydroergotamine mesylate (6190-39-2) is a full agonist at serotonin 5HT1B and 5HT1D receptors, IC50= 2 and 2.2 nM respectively1 and also at 5HT1A and 5HT1F receptors2. One of the oldest agents for treatment of migraine.3 Also acts as a potent vasoconstrictor and alpha-adrenergic antagonist.4
Description:
CAS Number: 6190-39-2<br></br>Chemical Name: (5’a,10a)-9,10-Dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)ergotaman-3′,6′,18-trione, mesylate<br></br>Molecular weight: 679.79<br></br>Formula: C33H37N5O5 • CH3SO3H<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC, NMR (Conforms)