bs-82670C
[Life Science]
CLP-3094
DATASHEET
Formulation Beige solid
Storage: -20°C
Product Information:
GPR142 is highly expressed in the pancreas and immune system and shares 33% homology with GPR1391. Endogenous agonists identified to date include aromatic amino acids such as tryptophan and phenylalanine2. CLP-3094 was identified as a potent and selective GPR142 antagonist with an IC50=2.3 M against 1 mM L-tryptophan. It inhibited insulin secretion from islets induced by L-tryptophan and other agonists and displayed anti-inflammatory activity in a mouse arthritis model.3
Description:
CAS Number: 312749-73-8<br></br>Chemical Name: 2-{[2-(4-Chlorophenoxy)ethyl]thio}-1H-benzimidazole<br></br>Molecular weight: 304.79<br></br>Formula: C15H13ClN2OS<br></br>Solubility: DMSO (45 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.