bs-82669C
[Life Science]
AC1903
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.
Description:
CAS Number: 831234-13-0<br></br>Chemical Name: 1-Benzyl-1H-benzoimidazol-2-yl)-furan-2-ylmethyl-amine<br></br>Molecular weight: 303.36<br></br>Formula: C19H17N3O <br></br>Solubility: DMSO (30 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.