bs-82667C
[Life Science]
CK-666
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 µM for human ARP2/3.1 Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process.2 CK-666 attenuates BBB dysfunction induced by methamphetamine3. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal4 and pathophysiology5.
Description:
CAS Number: 442633-00-3<br></br>Chemical Name: 2-Fluoro-N-[2-methyl-1H-indol-3-yl)ethyl]benzamide<br></br>Molecular weight: 296.34<br></br>Formula: C18H17FN2O <br></br>Solubility: DMSO (45 mg/ml) Ethanol (30 mg/ml)<br></br>Physical Properties: Cream-colored solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.