bs-82662C
[Life Science]
Mocetinostat
DATASHEET
Formulation White solid
Storage: RT
Product Information:
Class I, isoform-selective HDAC inhibitor, IC50s=0.15, 0.29, 1.66 and 0.59 μM for HDAC1, 2, 3 and 11 respectively.1 Induces hyperacetylation of histones, induces expression of the tumor suppressor p21WAF1 and inhibits proliferation of human cancer cells.2 Displays antifibrotic effects in ischemic heart failure.3 Attenuates the development of hypersensitivity in models of neuropathic pain.4 Active in vivo.5
Description:
CAS Number: 726169-73-9<br></br>Chemical Name: N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide<br></br>Molecular weight: 396.44<br></br>Formula: C23H20N6O<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.