DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.1,2 Nurr1 is a suppressor of NFkB-related neuroinflammatory genes in microglia and astrocytes and C-DIM 12 suppresses inflammatory signaling in these cells.3 Displays neuroprotective activity in a mouse model of progressive neurodegeneration with a strong neuroinflammatory component (50 mg/Kg, oral).4
Description:
CAS Number: 178946-89-9<br></br>Chemical Name: 3,3’-[(4-Chlorophenyl)methylene]bis[1H-indole]<br></br>Molecular weight: 356.85<br></br>Formula: C23H17ClN2<br></br>Solubility: DMSO (35 mg/ml) Ethanol (35 mg/ml)<br></br>Physical Properties: Orange solid<br></br>Purity: 98% by TLC, NMR (Conforms)