bs-82657C
[Life Science]
2-AAPA
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
Inhibits glutathione reductase and thioredoxin reductase,IC50s=6.7 and 8.7 µM respectively, and impairs mitochondrial function.1 May be used to induce a cellular model of thiol oxidative stress.2 Enhances sensitivity of cancer cell lines to X-ray irradiation.3 Induces G2/M cell cycle arrest by inducing thiol oxidative stress resulting in α-tubulin S-glutathionylation-mediated microtubule depolymerization.4 Improves limb revascularization by glutathionylation and subsequent stabilization of HIF-1α.5
Description:
CAS Number: 1133387-90-2<br></br>Chemical Name: R,R′-2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylthiocarbonylamino)-phenylthiocarbamoylsulfanyl]propionic acid, hydrate<br></br>Molecular weight: 518.65<br></br>Formula: C18H22N4O6S4<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by HPLC
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.