DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
Neuroregenerative and neuroprotective agent acting at components of the mitochondrial permeability transition pore (MPTP).1 Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in mice. Reduces ROS and NLRP3 inflammasome activation in a mouse model of intracerebral hemorrhage.2 Inhibits MPTP opening and protects neurons from apoptosis.3 Induces oligodendrocyte maturation in culture and promotes myelin regeneration in vivo in a rodent model.4
Description:
CAS Number: 22033-87-0<br></br>Chemical Name: Cholest-4-en-3-one oxime<br></br>Molecular weight: 399.65<br></br>Formula: C27H45NO<br></br>Solubility: DMSO (20 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)