bs-82653C
[Life Science]
Leu-Leu-OMe HBr
DATASHEET
Formulation Crystalline solid
Storage: -20°C
Product Information:
Leu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4
Description:
CAS Number: 16689-14-8<br></br>Chemical Name: Leucyl-leucine methyl ester hydrobromide<br></br>Molecular weight: 339.27<br></br>Formula: C13H26N2O3 HBr<br></br>Solubility: DMSO (35 mg/ml) Water (40 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMr (Conforms)
Size: 20 mg, 100 mg20 mg, 100 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.