DATASHEET
Formulation
white solid
Storage:
-20°C
Product Information:
A novel truncated analog of lipoxin A4 which retains anti-inflammatory activity.1 Inhibits LTB4-induced leukocyte chemotaxis, IC50=5 nM).1 Attenuates hemorrhagic shock-induced acute lung injury in a rat model.2 Displays hepatoprotective effects in acetaminophen-induced liver injury in mice.3 Limits inflammatory damage in the cerebral cortex and helps maintain blood brain barrier integrity in a rat model of ischemic stroke.4 Attenuates renal ischemia/reperfusion injury via activation of p38 MAPK/PPARα/HO-1 pathway.5
Description:
CAS Number: 78606-80-1<br></br>Chemical Name: (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate<br></br>Molecular weight: 192.21<br></br>Formula: C8H16O5<br></br>Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 99% by TLC NMR (Conforms)