DATASHEET
Formulation
Off-white to pale yellow solid
Storage:
-20°C
Product Information:
Arylhydrocarbon (AhR) receptor antagonist, IC50=30 nM.1 Blocks endogenous AhR agonist-induced differentiation of Th17 cells.2 Promotes expansion of human hematopoietic stem cells.3 Mitigates cytokine-mediated inflammatory signaling in human fibroblast-like synoviocytes.4 An important tool for probing the involvement of AhR in the toxicity of various environmental toxins such as TCDD and other dioxins.5
Description:
CAS Number: 301326-22-7<br></br>Chemical Name: 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl]-1H-pyrazole-5-carboxamide<br></br>Molecular weight: 333.39<br></br>Formula: C19H19N5O <br></br>Solubility: DMSO (25 mg/ml) Ethanol (10 mg/ml)<br></br>Physical Properties: Orange solid<br></br>Purity: 98% by TLC, NMR (Conforms)