bs-82641C
[Life Science]
Flavopiridol HCl
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase1. Potentiates (100-200 nM) PMA-induced apoptosis in HL-60 and U937 cells2. Potentiates the effects of topoisomerase I inhibitors by suppressing Rad51 expression in a p53-dependent manner. Displays potent antiviral activity against HIV-1 and HSV-1 in vitro4.
Description:
CAS Number: 131740-09-5<br></br>Chemical Name: 3-(3-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one, hydrochloride<br></br>Molecular weight: 438.30<br></br>Formula: C21H20ClNO5 HCl <br></br>Solubility: DMSO (40 mg/ml) Water (40 mg/ml)<br></br>Physical Properties: Light yellow solid<br></br>Purity: 98% by HPLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.