bs-82633C [Life Science]
ALLN
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Formulation White to off-white solid

Storage: -20°C

Product Information:

Cell-permeable, peptide aldehyde inhibitor of calpain I (Ki=190 nM), calpain II (Ki=150 nM), cathepsin L (Ki=0.5 nM) and other neutral cysteine proteases.1 Inhibits cell cycle progression at G1/S and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation.2 Inhibits proteolytic degradation of IκBα and IκBβ in RAW macrophages induced with LPS.3 Blocks AIF-mediated necroptosis.4 Cell permeable.

Description:

CAS Number: 110044-82-1<br></br>Chemical Name: Ac-Leu-Leu-Nle-CHO<br></br>Molecular weight: 383.53<br></br>Formula: C20H37N3O4<br></br>Solubility: DMSO (10 mg/ml) Ethanol (5 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)

Size: 5 mg, 25 mg5 mg, 25 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.