DATASHEET
Formulation
White or off-white solid
Storage:
RT
Product Information:
1,10-phenanthroline is a high affinity chelator of divalent metal ions and may be used to inhibit zinc metalloenzymes.1 It is a potent inhibitor of JAMM-type isopeptidases (DUBs) acting via chelation of an active site Zn2+. It may be used when preparing cell lysates for enrichment of ubiquitinated proteins which are especially sensitive to DUBs in the JAMM family.2,3
Description:
CAS Number: 18851-33-7<br></br>Chemical Name: <br></br>Molecular weight: 234.68<br></br>Formula: C12H8N2·HCl·H2O<br></br>Solubility: DMSO (5 mg/ml) Water (2 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC NMR (Conforms)