DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
Tenovin-1 activates p53 via inhibition of SIRT1 and SIRT2.1,2 Induces apoptosis in a variety of cancer cell lines including cutaneous T-cell lymphoma3 and melanoma4 among others5. Induces cellular senescence in cultured rat primary astrocytes6 as well as other cell types.
Description:
CAS Number: 380315-80-0<br></br>Chemical Name: N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide<br></br>Molecular weight: 369.48<br></br>Formula: C20H23N3O2S<br></br>Solubility: DMSO (10 mg/ml with warming)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC NMR (Conforms)