DATASHEET
Formulation
Off-white or beige solid
Storage:
RT
Product Information:
Potent inhibitor of prolyl 4-hydroxylase (IC50=2-4 μM)1. Inhibits collagen deposition via inhibition of collagen proline hydroxylation2,3. Subcutaneous injection of a 1,4-DPCA containing hydrogel into Swiss Webster mice that do not show a regenerative phenotype increased expression of HIF1α over 5 days. Multiple injections led to regenerative wound healing after ear hole punch injury4.
Description:
CAS Number: 331830-20-7<br></br>Chemical Name: 1,4-Dihydrophenonthrolin-4-one-3-carboxylic acid<br></br>Molecular weight: 240.22<br></br>Formula: C13H8N2O3<br></br>Solubility: DMSO 15 mg/ml<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC, NMR (Conforms)