DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
Q-VD-OPh is a potent and highly effective pan-caspase inhibitor with potent antiapoptotic activity which is not toxic to cells.1 Displays protective effects on brain damage and bacterial infection in a murine MCAO stroke model.2 Switches doxorubicin-induced apoptosis to an alternative default cell death mode marked by increased expression of senescence markers.3 Blocks staurosporin-induced differentiation of embryonic stem cells to cardiomyocytes.4 Trophoblasts treated with ceramide and Q-VD-OPh undergo necroptosis.5
Description:
CAS Number: 1135695-98-5<br></br>Chemical Name: Quinolyl-valyl-aspartyl-[2,6-difluorophenoxy]methyl ketone<br></br>Molecular weight: 513.49<br></br>Formula: C26H25F2N3O6<br></br>Solubility: DMSO (15 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 99% by HPLC NMR (Conforms)