DATASHEET
Formulation
White or off-white solid
Storage:
-20°C
Product Information:
YM-58483 is a CRAC (calcium release-activated calcium) channel blocker1, a prototypic store-operated calcium channel2. Inhibits antigen-induced histamine release via modulation of mast cell responses.3 Displays potent analgesic actions in various pain models in mice and is orally active.4 Inhibits T cell-mediated immune responses in vivo.5
Description:
CAS Number: 223499-30-7<br></br>Chemical Name: N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide<br></br>Molecular weight: 421.32<br></br>Formula: C15H9F6N5OS<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC NMR (Conforms)