bs-82611C
[Life Science]
Safinamide
DATASHEET
Formulation White or off-white solid
Storage: -20°C
Product Information:
A selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity over MAO-A.1 Displays anticonvulsant activity2 and protects against kainate-induced seizures and hippocampal neurodegeneration in rat models3. Reduces overactive glutamatergic signaling via use-dependent sodium channel blockade.4 A novel therapeutic for Parkinson’s disease with multiple modes of action.5 Effective as an add-on to dopamine agonist therapy in early Parkinson’s.6
Description:
CAS Number: 133865-89-1<br></br>Chemical Name: (S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide<br></br>Molecular weight: 302.34<br></br>Formula: C17H19FN2O2 <br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMr (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.