bs-82608C
[Life Science]
Z-DEVD-FMK
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5
Description:
CAS Number: 210344-95-9<br></br>Chemical Name: Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone<br></br>Molecular weight: 668.67<br></br>Formula: C30H41FN4O12<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Lyophilized solid<br></br>Purity: >98% by TLC, NMR (Conforms)
Size: 1 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.