bs-82604C
[Life Science]
Vildagliptin
DATASHEET
Formulation Red solid
Storage: -20°C
Product Information:
A potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that cleaves glucagon-like peptide 1 (GLP-1)1. Delaying the degradation of GLP-1 extends the action of insulin and suppressing the release of glucagon which results in reduction in elevated blood glucose levels (hyperglycemia)2. Clinically useful antidiabetic agent. Ameliorates cognitive deficits in streptozotocin-induced Alzheimers disease model3. Displays protective effects on β-cells by inhibition of ER stress in a mouse model4.
Description:
CAS Number: 274901-16-5<br></br>Chemical Name: (S)-1-[N-(3-Hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile<br></br>Molecular weight: 303.40<br></br>Formula: C17H25N3O2 <br></br>Solubility: DMSO (45 mg/ml) DMF (20 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.