DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
A novel endogenous tryptophan metabolite which acts as an aryl hydrocarbon receptor (AHR) agonist1. It drives IL-22 production by stimulating the differentiation of human and mouse T cells producing IL-221. Induces apoptosis in thymocytes2. Activates type 4 metabotropic glutamate receptors3. Counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells. Displays neuroprotective activity3.
Description:
CAS Number: 606-59-7<br></br>Chemical Name: 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid<br></br>Molecular weight: 300.22<br></br>Formula: C14H8N2O6 <br></br>Solubility: DMSO (30 mg/ml) DMF (25 mg/ml)<br></br>Physical Properties: Red solid<br></br>Purity: 98% by TLC NMR (Conforms)