DATASHEET
Formulation
White solid
Storage:
RT
Product Information:
Plerixafor is a highly selective CXCR4 antagonist (IC50 = 20-130 nM).1,2 Originally investigated as an HIV replication inhibitor.3 Plerixafor has been investigated for the treatment autoimmune diseases and various cancers.4 Clinically useful for the mobilization of hematopoietic stem cells in the treatment of blood cancers.
Description:
CAS Number: 110078-46-1<br></br>Chemical Name: 1,1’-[1,4-Phenylenebis-(methylene)]-bis(1,4,8,11-tetraazacyclotetradecane) octahydrochloride; <br></br>Molecular weight: 794.48<br></br>Formula: C28H54N8·8HCl<br></br>Solubility: Water (>25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)