DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
A competitive inhibitor of human lysosomal β-glucosidase, IC50 = 0.06 μM.1 Increases the activity of N370S mutant acid β-glucosidase (GlcCerase) in Gaucher fibroblasts.2 Displays a direct pharmacological chaperone effect greatly increasing the amount of newly synthesized GlcCerase that traffics out of the ER.2
Description:
CAS Number: 957230-65-8<br></br>Chemical Name: (3R,4R,5R)-5-Hydroxymethyl-3,5-piperidinediol tratrate<br></br>Molecular weight: 297.26<br></br>Formula: C6H13NO3 C4H6O6<br></br>Solubility: DMSO (2 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)