bs-82594C
[Life Science]
Nicotinamide
DATASHEET
Formulation Red solid
Storage: RT
Product Information:
Essential nutrient (amide form of Vitamin B3) that is incorporated into cofactors NADH/NAD+, important for ATP production and other key metabolic functions.1 Transiently inhibits SIRT1/SIRT3 through feedback inhibition (IC50 ~ 50 µM)2, but is quickly converted to NAD+ in cells3. Also inhibits certain kinases (e.g. ROCK and CK1), making it a regulator of hPSC pluripotency, survival, and differentiation.4 Inhibits differentiation and enhances functionality of hematopoietic stem/progenitor cells (HSPCs).5
Description:
CAS Number: 98-92-0<br></br>Chemical Name: Pyridine-3-carboxylic acid amide<br></br>Molecular weight: 122.13<br></br>Formula: C6H6N2O<br></br>Solubility: DMSO (50 mg/ml); water (50 ml)<br></br>Physical Properties: White solid<br></br>Purity: >99% by HPLC, NMR (Conforms)
Size: 1 g, 5 g1 g, 5 g
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.