DATASHEET
Formulation
Yellow solid
Storage:
-20°C
Product Information:
Inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis1. Originally reported as a selective inhibitor of 12-lipoxygenase, baicalein has since been shown to inhibit both 12-LO and 15-LO (IC50=0.64 µM for 12-LO and 1.6 µM for 15-LO)2. Displays antiinflammatory activity and inhibits adjuvant-induced arthritis. Also inhibits prolyl oligopeptidase (IC50=36 µM)3.
Description:
CAS Number: 491-67-8<br></br>Chemical Name: 5,6,7-Trihydroxyflavone<br></br>Molecular weight: 270.24<br></br>Formula: C15H10O5<br></br>Solubility: DMSO (15 mg/ml)<br></br>Physical Properties: Yellow or yellow-green solid<br></br>Purity: 98% by TLC, NMR (Conforms)