bs-82569C
[Life Science]
8-pCPT-2-O-Me-cAMP-AM
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
A potent, cell-permeable Epac (exchange protein directly activated by cAMP) activator1. Induces RAP1 activation and insulin secretion in pancreatic beta cell lines2-5. Induces vascular relaxation in rat mesenteric artery6. The acetoxymethyl ester confers increased cell-permeability and is cleaved by endogenous esterases to yield the active compound, 8-pCPT-2'-O-Me-cAMP. Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the acetoxymethyl ester and reduce cell permeability.
Description:
CAS Number: 1152197-23-3<br></br>Chemical Name: 8-(4-Chlorophenylthio)-2’-O-methyladenosine-3’,5’-cyclic monophosphate, acetoxymethyl ester<br></br>Molecular weight: 557.91<br></br>Formula: C20H21ClN5O8PS<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: solid<br></br>Purity: 97% by HPLC
Size: 100 ug100 ug
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.