bs-82567C [Life Science]
Chymostatin
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Formulation Off-white lyophilized solid (vial appear empty)

Storage: -20°C

Product Information:

A potent, competitive, slow-binding inhibitor of α-, β-, γ-, δ-chymotrypsin, papain and cathepsins B/G (chymotryptase-like serine proteases)1, Ki=9.36 and 13.1 nM for chymotrypsin and chymase2. Cathepsin G Ki=0.15 μM.3 Consists of a mixture of type A (L-Leu), B (L-Val) and C (L-Ile) forms.1 Decreases plasma and tissue levels of angiotensin II without lowering mean blood pressure in a hypertensive rat model.4 Commonly used in lysis buffers to prevent degradation of proteins. Typical working concentration is 6-60 µg/ml.

Description:

CAS Number: 9076-44-2<br></br>Chemical Name: [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu, B=Val, C=Ile]-phenylalaninal<br></br>Molecular weight: 605.00 (average)<br></br>Formula: C31H41N7O6<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 96% by TLC NMR (Conforms)

Size: 5 mg, 25 mg5 mg, 25 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.