bs-82562C [Life Science]
Ivabradine HCl
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Formulation White solid

Storage: -20°C

Product Information:

Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in the sinoatrial node (IC50’s: HCN1 = 2.05 µM, HCN2 = 2.29 µM, HCN3 = 2.51 µM, HCN4 = 2.15 µM).2

Description:

CAS Number: 148849-67-6<br></br>Chemical Name: 3-[3-[[(7S)-3,4-Dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride<br></br>Molecular weight: 505.05<br></br>Formula: C27H36N2O5·HCl <br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)

Size: 10 mg, 50 mg10 mg, 50 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.