bs-82542C
[Life Science]
Migalastat
DATASHEET
Formulation Beige solid
Storage: -20°C
Product Information:
Migalastat is a potent, selective, and orally available inhibitor of α-galactosidase A (IC50= 40 nM).1 It binds to mutant misfolded α-GalA shifting the folding behavior toward functional active conformation (pharmacological chaperone activity) followed by trafficking to the lysosomes.2 Migalastat is active broadly across species from Drosophila3 to human4. Clinically useful agent for Fabry disease.5
Description:
CAS Number: 75172-81-5<br></br>Chemical Name: (2R,3S,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol HCl<br></br>Molecular weight: 199.63<br></br>Formula: C6H13NO4 • HCl<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by TLC, NMR (Conforms)
Size: 1 mg, 5 mg 5 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.