DATASHEET
Formulation
Grey solid
Storage:
-20°C
Product Information:
Inhibits neutral endopeptidase 24.11 (NEP; Neprilysin; EC 3.4.24.11), Ki=2 nM.1 Also inhibits neprilysin 2 (Ki~2 nM).2 Also inhibits endothelin-converting enzyme (IC50 = 0.68 μM).3 Induces a dramatic increase in amyloid-beta levels in rodents.4
Description:
CAS Number: 119942-99-3<br></br>Chemical Name:
N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan • 2Na<br></br>Molecular weight: 587.47<br></br>Formula: C23H32N3O10P·2Na<br></br>Solubility: DMSO (>25 mg/ml) Water (>25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 97% by TLC NMR (Conforms)