bs-82519C
[Life Science]
FAK inhibitor 14
DATASHEET
Formulation Tan solid
Storage: -20°C
Product Information:
Selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. Exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo. Induces regression of pancreatic tumors2 and glioblastoma3. Displays antiangiogenic activity4.
Description:
CAS Number: 4506-66-5<br></br>Chemical Name: 1,2,4,5-Benzenetetramine tetrahydrochloride<br></br>Molecular weight: 284.02<br></br>Formula: C6H10N4 · 4HCl<br></br>Solubility: DMSO (20 mg/ml) water (15 mg/ml)<br></br>Physical Properties: Grey solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.