bs-82513C
[Life Science]
Stattic
DATASHEET
Formulation Orange solid
Storage: -20°C
Product Information:
STAT3 inhibitor. Inhibits binding of tyrosine-phosphorylated peptides to STAT3 SH2 domain and inhibiting STAT3 activation, dimerization and nuclear translocation1. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. Alkyates four cysteine residues on STAT32. Exhibits potent antitumor activity3. Protects against angiotensin II-induced vascular dysfunction and hypertension4. An extremely useful tool to probe involvement of STAT3 in cellular signaling.
Description:
CAS Number: 19983-44-9<br></br>Chemical Name: 6-Nitrobenzo[b]thiophene 1,1-dioxide<br></br>Molecular weight: 211.20<br></br>Formula: C8H5NO4S <br></br>Solubility: DMSO (10 mg/ml) Ethanol (1 mg/ml)<br></br>Physical Properties: Light yellow solid<br></br>Purity: 98% by TLC, NMr (Conforms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.