bs-82507C
[Life Science]
CUDC-101
DATASHEET
Formulation White solid - presented as thin film on glass vial
Storage: -20°C
Product Information:
A novel hybrid dual-acting HDAC and receptor tyrosine kinase inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2, IC50 = 4.4, 2.4 and 15.7 nM respectively.1 It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors.1,2
Description:
CAS Number: 1012054-59-9<br></br>Chemical Name: 7-((4-((3-Ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide<br></br>Molecular weight: 434.49<br></br>Formula: C24H26N4O4<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 99% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.