DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Clinically useful antidepressant that inhibits monoamine transporters DAT, NET, and SERT (Kis for dopamine uptake = 2.8, 1.4, 45 µM).1 Also acts as a noncompetitive antagonist at nicotinic acetylcholine receptors (AChRs).2 At higher concentrations (50 µM), stimulates pro-inflammatory cytokines and TLR2/TLR4 and JAK2/STAT3 in human peripheral blood mononuclear cells (PBMCs).3
Description:
CAS Number: 31677-93-7<br></br>Chemical Name: 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride<br></br>Molecular weight: 276.2<br></br>Formula: C13H18ClNO·HCl<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC, NMR (Conforms)