bs-82486C
[Life Science]
Veliparib 2HCl
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Potent and selective PARP-inhibitor with Ki values of 5.2 nM and 2.9 nM for PARP-1 and PARP-2, respectively.1 Restores sensitivity to DNA alkylator/methylator temozolomide in glioma cells and xenografts2, and enhances radiotherapy sensitivity in endometrial carcinoma cells3. Also improves sensitivity to DNA replication inhibitor cisplatin in human oral carcinoma cells.4
Description:
CAS Number: 912445-05-7<br></br>Chemical Name: 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide dihydrochloride<br></br>Molecular weight: 317.22<br></br>Formula: C13H16N4O·2HCl<br></br>Solubility: DMSO (30 mg/ml) Water (40 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.