bs-82474C
[Life Science]
Leflunomide
DATASHEET
Formulation Tan solid (MP = 168-170°C)
Storage: RT
Product Information:
A pyrimidine biosynthesis inhibitor DMARD (disease-modifying antirheumatic drug)1. Displays immunomodulatory activity inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH)2. Although the molecule directly responsible for DHODH is actually A77 1726, a metabolite of Leflunomide.
Rescues mice from acetaminophen-induced liver injury3.
Description:
CAS Number: 75706-12-6<br></br>Chemical Name: 5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide<br></br>Molecular weight: 270.21<br></br>Formula: C12H9F3N2O2<br></br>Solubility: DMSO (30 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (conforms)
Size: 50 mg, 250 mg50 mg, 250 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.