DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
A serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis.1 Reduces weight gain and improves metabol-ism in obese rodent models.2 In clinical use (in Japan) for pancreatitis.3 Inhibits influenza virus replication in human tracheal epithelial cells.4 Reduces infection of Calu-3 lung cells by SARS-CoV-2 (responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming.5
Description:
CAS Number: 56974-61-9<br></br>Chemical Name: 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid, ethyl ester, methanesulfonate <br></br>Molecular weight: 417.48<br></br>Formula: C16H23N3O4 ∙ CH3SO3H<br></br>Solubility: DMSO (50 mg/ml) Water (50 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)