bs-82432C
[Life Science]
Ansamitocin P3
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin1,2. Ansamitocin P3 is a maytansine analog which displays potent cytotoxicity against various human tumor cell lines2,3. Maytansine and its analogs cause extensive disassembly of microtubules and totally prevent tubulin spiralization4.
Description:
CAS Number: 66547-09-9<br></br>Chemical Name: <br></br>Molecular weight: 635.16<br></br>Formula: C32H43ClN2O9<br></br>Solubility: DMSO (50 mg/ml) Ethanol (30 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: >90% by TLC [1:9 CH3OH:CH2Cl2, Rf = 0.54] remainder is P-1, P-2 and P-4. NMR (Conforms)
Size: 1 mg, 5 mg 5 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.