DATASHEET
Formulation
White or off-white solid
Storage:
RT
Product Information:
Rho-associated kinase inhibitor (IC50 = 1.9 µM and 10.7 µM for Rho-associated kinase II and Rho-associated kinase respectively)1. Inhibits other kinases including cyclic nucleotide-dependent protein kinases.1 Reduces tryptamine-evoked vasopressor responses.2 attenuates bleomycin-induced pulmonary fibrosis in a mouse model.3 Clinically useful vasodilator.
Description:
CAS Number: 105628-07-7<br></br>Chemical Name: 1-(5-Isoquinolinesulfonyl)homopiperazine HCl<br></br>Molecular weight: 327.84<br></br>Formula: C14H17N3O2S · HCl<br></br>Solubility: DMSO (75 mg/ml) Water (100 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (conforms)