bs-82399C
[Life Science]
Bexarotene
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
A highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRα, β, γ respectively)1. Clinically useful antineoplastic agent for cutaneous T-cell lymphoma2 Causes complete regression of mammary carcinoma3. Bexarotene significantly increases clearance of soluble β-amyloid in a mouse Alzheimer′s model and increases cognitive ability4. Reverses apoE4-driven brain pathology and behavioral deficits in vivo5.
Description:
CAS Number: 153559-49-0<br></br>Chemical Name: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid<br></br>Molecular weight: 348.49<br></br>Formula: C24H28O2<br></br>Solubility: DMSO (60 mg/ml) Ethanol (10 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 10 mg, 100 mg10 mg, 100 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.