bs-82395C
[Life Science]
Tunicamycin
DATASHEET
Formulation Solution in DMSO
Storage: -20°C
Product Information:
Fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the fatty acid chain.
The structure shown above is for tunicamycin B (the C15 homolog)
Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis1. Causes endoplasmic reticulum stress-induced autophagy2 and unfolded protein response3. Arrests cell cycle in late G14.
Description:
CAS Number: 11089-65-9<br></br>Chemical Name: <br></br>Molecular weight: Avg 840.0<br></br>Formula: C38H62N4O16 (tun. B)<br></br>Solubility: DMSO (40 mg/ml) Ethanol (5 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 99% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.