bs-82393C
[Life Science]
Thiostrepton
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
Novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery as well as the activity of initiation factor-1 (IF-2)1-2. Displays antitumor activity. Induces apoptosis and cell cycle arrest in various tumor cells via downregulation of FOXM1 expression3.
Description:
CAS Number: 1393-48-2<br></br>Chemical Name: Fermentation product from Streptomyces azureus<br></br>Molecular weight: 1664.91<br></br>Formula: C72H85N19O18S5<br></br>Solubility: DMSO (15 mg/ml) Chloroform (5 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC and HPLC
Size: 1 g, 5 g1 g, 5 g
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.