DATASHEET
Formulation
Solution in ethanol (1mg/ml)
Storage:
-20°C
Product Information:
Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3.
Description:
CAS Number: 18378-89-7<br></br>Chemical Name: <br></br>Molecular weight: 1085.15<br></br>Formula: C52H76O24 <br></br>Solubility: DMSO (200 mg/ml) Ethanol (10 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by HPLC NMR (Conforms)