bs-82373C
[Life Science]
Cerulenin
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Fatty acid synthase (FAS) inhibitor. Binds to β-keto-acyl-ACP synthase (KAS; IC50=1.5 μM), thus inhibiting protein acylation at concentrations of 45-134 μM1. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream of, both leptin and melanocortin receptors2. Reduces nutrient-induced insulin release from normal rat islets3. Induces apoptosis in human melanoma A-375 cells4.
Description:
CAS Number: 17397-89-6<br></br>Chemical Name: 2,3-Epoxy-4-oxo-7,10-dodecadienamide<br></br>Molecular weight: 223.27<br></br>Formula: C12H17NO3 <br></br>Solubility: DMSO (10 mg/ml) Ethanol (10 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.