DATASHEET
Formulation
White solid
Storage:
RT
Product Information:
High affinity angiotensin AT1 receptor antagonist (Ki = 2.38 nM). Highly selective (30,000-fold) over AT2 receptors1,2. Normalizes the increased production of inflammatory cytokines in adipose and liver tissue in LPS-infused mice3. Clinically useful antihypertensive agent. Orally active.
Description:
CAS Number: 137862-53-4<br></br>Chemical Name: (S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-pentanamido]butanoic acid<br></br>Molecular weight: 435.52<br></br>Formula: C24H29N5O3<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 99% by TLC, NMR (conforms)