bs-82360C
[Life Science]
Ezetimibe
DATASHEET
Formulation White solid
Storage: RT
Product Information:
Inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter.1 Undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1.2 Inhibits dengue virus infection in Huh-7 cells by blocking cholesterol transport.3 Ameliorates steatohepatitis by activation of autophagy and inhibition of NLRP3 inflammasome.4
Description:
CAS Number: 163222-33-1<br></br>Chemical Name: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidine-2-one<br></br>Molecular weight: 409.43<br></br>Formula: C24H21F2NO3 <br></br>Solubility: DMSO (25 mg/ml) Ethanol (15 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 20 mg, 100 mg20 mg, 100 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.