bs-82354C
[Life Science]
2',3'-cGAMP
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
2',3'-cGAMP (CAS 1441190-66-4) is an endogenous STING (stimulator of interferon genes) agonist.1 Produced from ATP and GTP via the action of cGMP-AMP synthase (cGAS) which acts as a cytosolic DNA sensor.2,3 Induces autophagy which is a mechanism for clearance of DNA and viruses in the cytosol.4 DNA damage stimulates 2’,3’-cGAMP which stimulates an inflammatory response.5
Description:
CAS Number: 1441190-66-4<br></br>Chemical Name: Adenylyl-(3’5’)-2’guanylic acid, cyclic nucleotide, disodium salt<br></br>Molecular weight: 718.38<br></br>Formula: C20H22N10O13P2·2Na<br></br>Solubility: DMSO (>25 mg/ml) Water (10 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 1 mg,200 ug200 ug
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.