DATASHEET
Formulation
Yellow solid
Storage:
-20°C
Product Information:
A potent and selective inhibitor of the autophagy kinase ULK-1, IC50=108 and 711 nM for ULK1 and 2 respectively.1 Suppresses autophagy induced by mTOR inhibitors and thus synergizes with mTOR inhibitors to induce apoptosis and cell death in tumor cells.1
Description:
CAS Number: 1884220-36-3<br></br>Chemical Name: 2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide<br></br>Molecular weight: 489.32<br></br>Formula: C21H21BrN4O5<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC/TLC NMR (Conforms)