bs-82346C
[Life Science]
Herboxidiene
DATASHEET
Formulation Pale yellow solid
Storage: -20°C
Product Information:
A novel polyketide fermentation product produced by Streptomyces chromofuscus, originally discovered by screening for herbicidal activity. Potent and selective inhibitor of spliceosome subunit SF3b.2 Specifically targets SAP155, a subunit of SF3b responsible for pre-mRNA splicing.3 Displays anti-angiogenic activity via down-regulation of VEGFR-2 and HIF-1α.4 Spliceosome inhibitors have attracted enormous attention due to their potential use in cancer treatment.5
Description:
CAS Number: 142861-00-5<br></br>Chemical Name: <br></br>Molecular weight: 438.60<br></br>Formula: C25H42O6<br></br>Solubility: DMSO or ethanol<br></br>Physical Properties: White solid<br></br>Purity: 97% by HPLC NMR (Conforms)
Size: 1 mg,200 ug200 ug
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.